| Home Team | Score | | Score | Away Team |
| 11 October 2009 |
| Northants Lightning | 54 |
v
| 37 | Hatfield Fliers |
| 18 October 2009 |
| Hinckley & Bosworth Lady Hoops | 15 |
v
| 82 | Northants Lightning |
| 24 October 2009 |
| Northants Lightning | 70 |
v
| 49 | Birmingham Force |
| 07 November 2009 |
| Doncaster Panthers | 80 |
v
| 35 | Northants Lightning |
| 14 November 2009 |
| Hatfield Fliers | 40 |
v
| 42 | Northants Lightning |
| 21 November 2009 |
| Northants Lightning | 35 |
v
| 54 | Doncaster Panthers |
| 05 December 2009 |
| Nottingham Wildcats | 73 |
v
| 56 | Northants Lightning |
| 12 December 2009 |
| City Of Sheffield Hatters | 89 |
v
| 79 | Northants Lightning |
| 16 January 2010 |
| Northants Lightning | 10 |
v
| 111 | Hinckley & Bosworth Lady Hoops |
| 23 January 2010 |
| Birmingham Force | 65 |
v
| 85 | Northants Lightning |
| 30 January 2010 |
| Northants Lightning | 31 |
v
| 63 | Nottingham Wildcats |
| 06 February 2010 |
| Northants Lightning | 54 |
v
| 55 | Exeter Eagles |
| 13 February 2010 |
| Northants Lightning | 51 |
v
| 38 | Hatfield Fliers |
| 20 February 2010 |
| Doncaster Panthers | 54 |
v
| 47 | Northants Lightning |
| 07 March 2010 |
| Northants Lightning | 48 |
v
| 59 | City Of Sheffield Hatters |
| 13 March 2010 |
| Exeter Eagles | 57 |
v
| 52 | Northants Lightning |
| 27 March 2010 |
| Haringey Angels | 104 |
v
| 39 | Haringey Angels |