| Home Team | Score | | Score | Away Team |
| 11 October 2009 |
| Bristol Storm | 31 |
v
| 81 | Northants Lightning |
| 17 October 2009 |
| Northants Lightning | 40 |
v
| 73 | Solent Suns |
| 25 October 2009 |
| Woking Blackhawks | 70 |
v
| 57 | Northants Lightning |
| 08 November 2009 |
| Northants Lightning | 61 |
v
| 37 | Chiltern Pumas |
| 14 November 2009 |
| City of Birmingham Force | 67 |
v
| 46 | Northants Lightning |
| 06 December 2009 |
| Solent Suns | 72 |
v
| 42 | Northants Lightning |
| 12 December 2009 |
| Northants Lightning | 71 |
v
| 49 | Woking Blackhawks |
| 19 December 2009 |
| Northants Lightning | 40 |
v
| 96 | Sevenoaks Suns |
| 16 January 2010 |
| Northants Lightning | 72 |
v
| 69 | City of Birmingham Force |
| 24 January 2010 |
| Hinckley & Bosworth Lady Hoops | 35 |
v
| 76 | Northants Lightning |
| 30 January 2010 |
| Northants Lightning | 93 |
v
| 27 | Bristol Storm |
| 06 February 2010 |
| Northants Lightning | 48 |
v
| 83 | Solent Suns |
| 14 February 2010 |
| Woking Blackhawks | 71 |
v
| 69 | Northants Lightning |
| 27 February 2010 |
| Northants Lightning | 70 |
v
| 23 | Hinckley & Bosworth Lady Hoops |
| 28 February 2010 |
| City of Birmingham Force | 69 |
v
| 36 | Northants Lightning |
| 14 March 2010 |
| Bristol Storm | 36 |
v
| 67 | Northants Lightning |
| 20 March 2010 |
| Northants Lightning | 20 |
v
| 0 | Hinckley & Bosworth Lady Hoops |
| 27 March 2010 |
| City Of Sheffield Hatters | 69 |
v
| 38 | Northants Lightning |